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目的对比观察非手术疗法治疗不同TNM分期肝癌的疗效。方法716例肝癌患者按非手术疗法[经皮无水酒精瘤内注射(PEI)、射频消融术(RFA)、电化学治疗(ECT)、微波治疗(PMCT)、经导管肝动脉化疗栓塞(TACE)]分5组进行治疗,对比观察TNM不同分期患者非手术疗法的1、2、3、5年生存率。结果5类非手术疗法的1、2、3、5年生存率组间比较显示:TNMⅠ~Ⅱ期病例1年生存率组间差异无统计学意义(P>0.05),2、3、5年生存率组间差异有统计学意义(P<0.05),其中TACE组低于其他组。TNMⅢ期病例1、2、3、5年生存率差异无统计学意义(P>0.05)。TNMⅣ期病例1、2年生存率差异无统计学意义(P>0.05)。结论PEI、RFA、ECT、PMCT、TACE等非手术疗法是肝癌治疗的有效手段,在临床治疗中要根据肿瘤分期、病灶大小、肝功能情况合理的选择非手术治疗方法。
Objective To compare the efficacy of non-surgical treatment of different TNM staging of liver cancer. Methods 716 patients with hepatocellular carcinoma (HCC) underwent non-surgical therapy (PEI, RFA, ECT, PMCT, TACE )] Were divided into 5 groups for treatment. The 1, 2, 3, 5-year survival rates of non-surgical treatment of TNM patients with different staging were observed. Results Comparisons of 1, 2, 3, 5-year survival rates of 5 non-surgical treatments showed that there was no significant difference in 1-year survival rates between TNM Ⅰ and Ⅱ cases (P> 0.05), 2, 3 and 5 years There was a significant difference in survival rate between the two groups (P <0.05). The TACE group was lower than the other groups. There was no significant difference in the 1, 2, 3, 5-year survival rates in TNM Ⅲ cases (P> 0.05). There was no significant difference in the 1-year and 2-year survival rates between TNM Ⅳ cases (P> 0.05). Conclusion Non-surgical treatment such as PEI, RFA, ECT, PMCT and TACE is an effective method for the treatment of hepatocellular carcinoma. In clinical treatment, it is necessary to choose non-surgical treatment according to tumor stage, lesion size and liver function.