目的探讨早产儿血清CK、CKMB、LDH、AST、α-HBDH参考值。方法对极早早产儿和晚期早产儿于生后出生48～72h病情稳定时采集静脉血化验CK、CKMB、LDH、AST、α-HBDH。结果早产儿的参考值明显高于成人,而且波动范围宽,并随胎龄的增大上限逐渐降低。结论早产儿的参考值明显高于成人,临床工作中应采用早产儿参考值。 Objective To investigate the serum CK, CKMB, LDH, AST and α-HBDH in preterm infants. Methods Venous blood tests CK, CKMB, LDH, AST, and α-HBDH were collected during the first 48 h to 72 h postpartum in extremely premature infants and late preterm infants. Results The reference value of preterm children was significantly higher than that of adults, and the range of fluctuation was wide and gradually decreased with the increase of gestational age. Conclusion The reference value of premature children is obviously higher than that of adults, and the reference value of premature children should be used in clinical work.