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目的:观察复方异丙托溴氨雾化溶液联合布地奈德压缩雾化吸入治疗毛细支气管炎的临床疗效。方法:将我院2009年7月至2012年1月收治的90例毛细支气管炎患儿依家长意愿随机分为两组,对照组45例采用常规综合治疗,对照组45例在综合治疗的基础上,增加复方异丙托溴氨雾化溶液联合布地奈德压缩雾化吸入治疗,观察两组的临床症状、体征改变情况。结果:治疗组的总有效率明显高于对照组,两组差异有统计学意义(P<0.05);治疗组在呼吸困难、喘憋、肺部啰音消失、住院日及治愈率方面与对照组比,均有显著性差异(P<0.05)。结论:复方异丙托溴氨雾化溶液联合布地奈德压缩雾化吸入治疗毛细支气管炎疗效显著,能迅速改善临床症状,缩短病程,且不良反应较少,方便安全,值得临床借鉴。
Objective: To observe the clinical efficacy of compound ipratropium bromide nebulization solution combined with budesonide compressed atomization inhalation in the treatment of bronchiolitis. Methods: Ninety patients with bronchiolitis admitted to our hospital from July 2009 to January 2012 were randomly divided into two groups according to parents’ wishes. In the control group, 45 cases were treated with conventional comprehensive treatment and 45 cases in the control group were treated on the basis of comprehensive treatment , Increase the compound ipratropium bromide atomization solution combined with budesonide compressed atomization inhalation treatment, the clinical symptoms and signs of two groups were observed changes. Results: The total effective rate of the treatment group was significantly higher than that of the control group (P <0.05). The treatment group had no significant difference in the aspects of dyspnea, wheezing, disappearance of pulmonary rales, hospitalization days and the cure rate There was significant difference between the two groups (P <0.05). Conclusion: The combination of ipratropium bromide atomizing solution and budesonide compressed atomization inhalation for the treatment of bronchiolitis has significant curative effect, which can rapidly improve the clinical symptoms and shorten the course of the disease with less adverse reactions, which is convenient and safe and worthy of clinical reference.