胸腔内置微管引流治疗结核性胸膜炎的疗效观察

来源 :中国药物经济学 | 被引量 : 0次 | 上传用户:genius0728
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目的评价微管引流治疗结核性胸膜炎并胸腔积液的疗效和不良反应。方法选取我院2008年1月至2010年1月138例结核性胸腔积液患者,随机分成两组,对照组采用传统间断、反复穿刺抽液治疗,观察组采用胸腔内置微导管持续引流胸水治疗,两组均胸腔注射相同药物。分析强化治疗阶段内胸水吸收程度、时间、胸膜肥厚及不良反应。结果两种方法均能减少胸腔积液量,但观察组胸水完全吸收时间平均7.6 d,明显优于对照组(P<0.01),胸膜增厚粘连发生率与对照组比较差异有统计学意义(P<0.01),不良反应发生未见明显增加,差异无统计学意义(P>0.05)。结论使用微导管引流治疗结核性胸膜炎并胸腔积液疗效确切、安全,优于传统反复胸腔穿刺抽液术。 Objective To evaluate the efficacy and adverse reactions of microtubule drainage in the treatment of tuberculous pleurisy and pleural effusion. Methods A total of 138 patients with tuberculous pleural effusion from January 2008 to January 2010 in our hospital were randomly divided into two groups. The control group was treated with intermittent and repeated puncture aspirate liquid. The observation group was treated with continuous drainage of pleural fluid through microcatheter , Both groups were injected with the same drugs chest. Analysis of intensive treatment of pleural effusion within the degree of time, pleural hypertrophy and adverse reactions. Results Both methods could reduce pleural effusion, but the total pleural effusion time in the observation group was 7.6 days on average, which was significantly better than that in the control group (P <0.01). The incidence of pleural thickening and adhesion was significantly different from that in the control group P <0.01), no significant increase in adverse reactions, the difference was not statistically significant (P> 0.05). Conclusions The use of microcatheter drainage in the treatment of tuberculous pleurisy and pleural effusion is effective and safe, which is superior to the traditional recurrent thoracentesis.
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