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目的研究血B型钠尿肽(BNP)和急性心肌梗死的早期介入治疗和预后关系。方法选取2013年4~7月我院收治的急性心肌梗死患者120例,按照治疗方法的不同随机分为试验1、2组和对照组各40例。试验1组患者予入院6h内介入治疗,试验2组予入院6h后介入治疗,对照组患者采用常规保守治疗,观察3组患者的血BNP水平和预后情况。结果进行试验之前3组各项指标一致,没有明显差异。在采取不同研究治疗方案后,2个试验组基础BNP水平较对照组明显下降(P<0.05),试验1组较试验2组也有明显的下降(P<0.05)。同时,与没有发生BNP患者相比,已经发生了此病症的患者其在发病了3个月之后所产生的心血管事件明显增多,P<0.05。结论对于急性心肌梗死患者来说,其发病1周之后BNP、心功能显著,2者之间表现为正相关,在患者发病时候血BNP明显的升高,所以能够有效的预防可能发生的心血管事件以及症状,很显然早期介入治疗能够改善患者的BNP水平。
Objective To study the relationship between early interventional therapy and prognosis of blood B-type natriuretic peptide (BNP) and acute myocardial infarction. Methods A total of 120 acute myocardial infarction patients admitted to our hospital from April to July in 2013 were randomly divided into two groups according to the different treatment methods: experimental group 1 and group 2 and control group 40 cases each. The patients in trial 1 were treated 6 h after admission. The patients in trial 2 were treated 6 h after admission. The patients in control group were treated with conventional conservative therapy. The levels of BNP and the prognosis of the patients were observed. Results Before the test, the three groups of indicators were the same, there was no obvious difference. The BNP levels in the two experimental groups were significantly lower than those in the control group (P <0.05). The experimental group 1 had a significant decrease (P <0.05) compared with the experimental two groups. At the same time, patients who had developed this condition had significantly increased cardiovascular events 3 months after onset compared with those without BNP (P <0.05). Conclusions For patients with acute myocardial infarction, BNP and cardiac function are significant after 1 week of onset, and the two are positively correlated with each other. The BNP level is significantly elevated at the onset of the disease, so it can effectively prevent cardiovascular events that may occur Incidents and symptoms, it is clear that early intervention can improve the patient’s BNP levels.