目的了解扩大国家免疫规划前后“六苗”基础接种率的变化,为制定免疫规划相关政策提供依据。方法 2008和2012年分别在深圳市开展儿童国家免疫规划疫苗接种率的调查,依据预防接种门诊地理位置分布按比例抽取预防接种门诊,共抽取238间社区健康服务中心,每间调查不低于30名儿童,两次共调查6 163名儿童。结果 2012年深圳市儿童“六苗”接种率分别为卡介苗(99.6%)、乙肝疫苗(99.1%)、脊灰疫苗(99.6%)、百白破疫苗(99.2%)、麻疹疫苗(99.5%)、乙脑疫苗(98.7%)、“六苗”基础免疫全程接种率(97.4%)均高于2008年(卡介苗、乙肝疫苗、脊灰疫苗、百白破疫苗、麻疹疫苗、乙脑疫苗、“六苗”基础免疫全程接种率分别为94.0%、93.8%、94.6%、93.6%、94.3%、93.1%、89.4%),差异均有统计学意义(P<0.01)。结论通过实施扩大国家免疫规划可以提高儿童免疫接种率。 Objective To understand the changes of the basic vaccination rate of “Six seedlings” before and after the expansion of the national immunization program and provide the basis for formulating the relevant policies of the immunization program. Methods In 2008 and 2012 respectively, the vaccination coverage of children’s immunization programs in Shenzhen was surveyed. According to the geographical distribution of vaccination clinics, preventive immunization clinics were drawn proportionally. A total of 238 community health service centers were selected, each of which had a minimum of 30 Two children were enrolled in a total of 6 163 children. Results The vaccination rates of children and six seedlings in Shenzhen in 2012 were 99.6%, 99.1%, 99.6%, 99.6%, 99.2%, 99.5% (98.7%) and the whole vaccination rate of basic vaccination (97.4%) of “Six seedlings” were higher than those of 2008 (BCG, hepatitis B vaccine, polio vaccine, diphtheria vaccine, measles vaccine, The total vaccination rates of brain vaccine and “six seedlings” were 94.0%, 93.8%, 94.6%, 93.6%, 94.3%, 93.1%, 89.4%, respectively). The difference was statistically significant (P <0.01). Conclusion Child immunization coverage can be increased through the implementation of expanded national immunization programs.