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药物代谢动力学是研究药物在体内的吸收、分布、排泄以及结构转化的速率过程。所有这些速率过程都影响药物在体内之浓度变化与在体内滞留时间,药物的治疗效果,由药物在体内的浓度来决定,此浓度以药物在血液中的浓度水平来表示。药物的疗效,除了与药物本性有关外,并与给药一途径、剂型、剂量及给药方案有关,本文拟就如何选择适宜的给药途径、剂型、剂量及给药方案,使
Pharmacokinetics is the study of drug absorption, distribution, excretion and the rate of structural conversion in the body. All of these rate processes affect the change in concentration of the drug in the body and the residence time in the body. The therapeutic effect of the drug is determined by the concentration of the drug in the body, expressed as the concentration of the drug in the blood. The curative effect of the drug is not only related to the nature of the drug, but also related to the route of administration, dosage form, dosage and dosage regimen. In this paper, how to choose the appropriate route of administration, formulation, dosage and dosage regimen,