米非司酮别名息隐、含珠停,为人工合成的甾体类化合物,是炔诺酮衍生物,为新型抗孕激素药。其与黄体酮受体的亲和力是孕酮的5倍,与糖皮质激素受体的结合力是地塞米松的3倍,与雄激素受体的结合力是睾酮的1/4,无雌激素、雄激素及孕激素活性,无抗盐皮质激素及抗雌激素活性,有微弱的抗雄激素活性。 Mifepristone alias interest hidden, containing beads stop for the synthesis of steroidal compounds, is a derivative of norethindrone, a new antiprogestin drug. Its progesterone receptor affinity is 5 times progesterone, and glucocorticoid receptor binding is 3 times that of dexamethasone, and androgen receptor binding testosterone is 1/4, no estrogen , Androgen and progestin activity, no anti-mineralocorticoid and anti-estrogen activity, a weak anti-androgen activity.