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地奥脂必妥(下称脂必妥)是一种降脂新药,临床应用中发现具有良好的通便功能。自1996年3月至1996年8月,我们用该药治疗功能性便秘50例,收到良好疗效,现总结如下。 1 临床资料 1.1 病例选择:80例便秘病人均经临床X线钡餐透视及/或纤维胃镜检查,排除了器质性疾病。分为2组:治疗组50例,男23例,女27例,年龄29—64(46±8)岁,排便周期4—12天(8.4±3.8天),病程6个月—13年(3.6±2.9)。对照组30例,其性别、年龄、排便周期与治疗组无差异(P>0.05),有可比性。 1.2 方法:所有病人均在门诊由同一医师进行治疗观察。治疗组服脂必妥1.05g/次,每日3次;对照组服通便灵1.0g/次,每日3次,疗程均为1个月。治疗期间不用助消化剂及胃肠动力药。疗程结束后复查血、尿常规及肝肾功能等,并记录排便周期、临床症状及副作用等。
Dioprolol (hereinafter referred to as Lipid) is a lipid-lowering drug, found in clinical applications has a good laxative function. From March 1996 to August 1996, we used the drug to treat 50 cases of functional constipation, received good results, are summarized as follows. 1 Clinical data 1.1 Case Selection: 80 cases of patients with constipation by clinical X-ray barium meal and / or fiber endoscopy, ruled out organic disease. The patients in the treatment group were divided into two groups: 50 cases in the treatment group, 23 males and 27 females, aged 29-64 (46 ± 8) years, defecation cycles 4-12 days (8.4 ± 3.8 days) and duration of 6 months to 13 years 3.6 ± 2.9). The control group of 30 cases, the sex, age, defecation cycle and the treatment group no difference (P> 0.05), comparable. 1.2 Methods: All patients were treated by the same doctor in the clinic. The treatment group was given Lipid 1.05g / time 3 times a day. The control group received 1.0g / time of Stupid Pharmacy 3 times daily for 1 month. Do not help during treatment of digestive and gastrointestinal motility drugs. After the end of treatment, check the blood, urine and liver and kidney function, and record the defecation cycle, clinical symptoms and side effects.