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用ELISA法检测微量尿白蛋白(Alb)、IgG、IgA、IgM,用酶标抗体染色作尿管型蛋白成份分析,对123例原发性高血压患者进行了观察。结果提示,高血压患者尿Al1b、IgG、IgA、IgM显著升高,与疾病严重程度、血压高低、病程长短有密切关系。治疗后可降至正常。患者管型中不含IgG、IgA、IgM与Alb。两法联合应用,有助于区别肾性与原发性高血压,并可对原发性高血压的肾功能改变进行早期预测与监护。
Urinary albumin (Alb), IgG, IgA and IgM were detected by ELISA, and the contents of urinary protein were analyzed by enzyme-linked immunosorbent assay. 123 patients with essential hypertension were observed. The results suggest that urinary Al1b, IgG, IgA, IgM significantly elevated in patients with hypertension, and the severity of the disease, blood pressure, the duration of the disease are closely related. After treatment can be reduced to normal. Patient tube type does not contain IgG, IgA, IgM and Alb. The combination of the two methods can help distinguish between renal and essential hypertension and predict and monitor changes in renal function in patients with essential hypertension.