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目的探讨女性内胚窦瘤的临床特征、诊断及治疗方法。方法对37例女性内胚窦瘤患者临床资料进行回顾性分析。结果女性内胚窦瘤主要表现为阴道出血、流液及腹部胀痛、下腹部包块,血清甲胎蛋白异常增高,手术联合化疗是治疗内胚窦瘤的主要方法。结论纤维软性宫腔镜检查可作为疑诊内胚窦瘤的辅助检查手段;手术方式可根据是否保留生育功能或肿瘤临床分期而决定;手术+化疗是内胚窦瘤首选治疗方法。
Objective To investigate the clinical features, diagnosis and treatment of female endodermal sinus tumor. Methods The clinical data of 37 female patients with endodermal sinus tumor were analyzed retrospectively. Results Female endodermal sinus tumors mainly manifested as vaginal bleeding, fluid and abdominal pain, lower abdominal mass, serum alpha-fetoprotein abnormalities increased, surgery combined with chemotherapy is the main method of treatment of endodermal sinus tumor. Conclusions Fibrous soft hysteroscopy can be used as an auxiliary examination method for suspected endodermal sinus tumor. The surgical method can be decided according to whether to retain the reproductive function or the clinical staging of the tumor. Surgery and chemotherapy are the preferred treatment for endodermal sinus tumor.