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骨髓增生异常综合征(MDS)是造血干细胞的异质性疾病,其外周血表现为一系、两系或三系减少,骨髓以病态造血为特征,具有向白血病转化的风险性。目前 MDS 的诊断还是以形态学为基础,结合临床及染色体的检查及随访来确诊。但是形态学的检查具有主观性,且细胞形态的改变有时会受药物等因素的影响而干扰诊断,而 MDS 患者也不会100%出现染色体异常,一些 RA 患者与某些再生障碍性贫血
Myelodysplastic syndrome (MDS) is a heterogeneous disease of hematopoietic stem cells. Its peripheral blood is characterized by one, two or three lines reduction. The bone marrow is characterized by pathological hematopoiesis and has the risk of transforming to leukemia. The diagnosis of MDS is still based on morphological, combined with clinical and chromosomal examination and follow-up to confirm. However, morphological examination has the subjectivity, and changes in cell morphology may sometimes be affected by drugs and other factors interfere with the diagnosis, and MDS patients will not be 100% chromosomal abnormalities, some RA patients with some aplastic anemia