本文报导一位老年男性病人患原发性骨髓纤维病变,又于躯干部发生许多丘疹相维在面部又出现群集的皮下小结节。这些皮肤损害表示的组织学特征是共有三种成分组成的骨髓外造血,就是红髓细胞髓细胞样的及多核巨细胞的成分,从来还没有发现合并皮肤损害的报导。皮肤产生造血只是在生命胚胎的早期因此除了在罕见的红白血病病例外,通常在皮肤上不发生不成熟的髓细胞样和红髓细胞浸润。骨髓纤维病变被认为属于骨髓增生的疾病,类似 This article reports on an elderly male patient with primary myelofibrosis and many papules in the trunk that appear to cluster in the face again with subcutaneous nodules. These histological features of skin lesions represent a combination of three components of extramedullary hematopoiesis, the components of myeloid and multinuclear giant cells of the red pulp cells, and no reports of skin lesions have been reported. Skin-forming hematopoiesis occurs only early in the life embryo so immature myeloid and red pulp cell infiltrates are usually not present on the skin, except in rare cases of erythroleukemia. Myelofibrosis is considered to be a disease of myeloproliferation and is similar