组织工程近年来已成为眼表重建研究的热点。组织工程材料在眼表重建的应用包括胶原及复合材料、羊膜复合体、壳聚糖复合材料及人工合成可降解材料(聚乳酸、聚羟基乙酸)等诸多材料。本文将介绍上述组织工程材料在眼表重建实验和临床应用的研究现状及进展。 Tissue engineering has become a hot spot in the research of ocular surface reconstruction in recent years. Tissue engineering materials in the reconstructive ocular surface include collagen and composite materials, amnion complex, chitosan composite materials and synthetic biodegradable materials (polylactic acid, polyglycolic acid) and many other materials. This article will introduce the above tissue engineering materials in ocular surface reconstruction experiments and clinical application of research status and progress.