反复自然流产(recurrent。r repetitive Sponta-neous ahortion,RSA)是指连续发生3次或3次以上的自然流产,发生率为0.4%一1.0%,若按连续发生2次计算,则为5%。RsA原因有解剖、内分泌、感染、染色体、遗传等,其中40%一80%原因不明的RsA可能与免疫因素有关[l],是母体免排斥胎儿的 Recurring spontaneous abortion (recurrent.r repetitive Sponta-neous ahortion, RSA) refers to the continuous occurrence of 3 or more times of spontaneous abortion, the incidence of 0.4% to 1.0%, if the occurrence of 2 consecutive calculations, then 5% . RsA causes anatomical, endocrine, infections, chromosomes, heredity, etc., of which 40% to 80% of unexplained RsA may be related to immune factors [1], is the mother immune rejection of the fetus