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目的探讨新疆维吾尔自治区汉族、维吾尔族妇女乳腺癌发病的影响因素。方法于2008年6月-2009年10月对新疆医科大学附属肿瘤医院病理确诊的433例汉族和103例维吾尔族乳腺癌患者进行1∶1病例对照研究,采用单因素和多因素条件Logistic回归进行统计分析。结果汉族和维吾尔族妇女乳腺癌发病共同危险因素为绝经年龄晚、肿瘤家庭史、遭遇重大挫折,其中腌渍食物摄入次数多为汉族妇女乳腺癌单独的危险因素(OR=2.729,95%CI=1.762～4.228),肉类摄入次数多(OR=2.744,95%CI=1.784～4.221)是维吾尔族妇女乳腺癌单独的危险因素;月经规律(OR=0.475,95%CI=0.252～0.893)、蔬菜摄入次数多(OR=0.498,95%CI=0.348～0.712)为汉族妇女乳腺癌保护因素;初潮年龄晚(OR=0.676,95%CI=0.536～0.812),母乳喂养持续时间长(OR=0.496,95%CI=0.269～0.618),活产次数多(OR=0.306,95%CI=0.097～0.965)为维吾尔族妇女乳腺癌保护因素。结论新疆汉族、维吾尔族女性乳腺癌发病影响因素存在差异。
Objective To investigate the influencing factors of breast cancer in Han and Uighur women in Xinjiang Uygur Autonomous Region. Methods From June 2008 to October 2009, 433 cases of Han and 103 cases of Uighur breast cancer diagnosed in the Affiliated Tumor Hospital of Xinjiang Medical University were studied by 1: 1 case-control study, using single factor and multivariate Logistic regression Statistical Analysis. Results The common risk factors of breast cancer in Han and Uygur women were late menopause, family history of cancer, and suffered major setbacks. The number of pickled foods was the only risk factor for breast cancer in Han women (OR = 2.729, 95% CI = (OR = 2.744, 95% CI = 1.784-4.221) were the risk factors of breast cancer in Uighur women. The regularity of menstruation (OR = 0.475, 95% CI = 0.252-0.893) (OR = 0.498, 95% CI = 0.348-0.712) were the protective factors for breast cancer in Han women. The age of menarche was late (OR = 0.676, 95% CI = 0.536-0.812) and the duration of breastfeeding was longer OR = 0.496, 95% CI = 0.269-0.618), and more live births (OR = 0.306,95% CI = 0.097-0.965) were the protective factors of breast cancer in Uighur women. Conclusion The incidence of breast cancer in Han and Uygur women in Xinjiang is different.