论文部分内容阅读
慢性接触镉离子的主要危险是肾脏受损。但镉的这种毒作用机理至今还不清楚。接触镉后,需过一段时间才会出现肾脏损害。有人认为,镉在肾皮质中缓慢蓄积超过临界浓度时,其毒作用才会在细胞内显现出来,所以肾脏毒性也就迟缓出现。也有人认为,肾损害可能是因为循环中镉金属硫蛋白(Cd-Th)浓度增加所致,而这些Cd-Th是在其他器官、组织(首先
The main risk of chronic exposure to cadmium is kidney damage. However, the toxic mechanism of cadmium so far is still not clear. After exposure to cadmium, it may take a while before kidney damage occurs. Some people think that cadmium in the renal cortex in the accumulation of more than the critical concentration, the toxic effects will be revealed in the cells, so the toxicity of the kidney also appeared slowly. It is also suggested that kidney damage may be due to an increase in circulating levels of cadmium metallothionein (Cd-Th), which are found in other organs, tissues (first