纯红细胞再生障碍性贫血(PRCA)是一种以正细胞正色素贫血、网织红细胞减低和骨髓幼红细胞显著减少或缺如为特征的综合征,包括先天性PRCA(Diamond-Blackfan贫血)和获得性PRCA。其中,获得性PRCA又可分为原发性和继发性,原发性PRCA可能与自身免疫有关,也可见于白血病前期,大多数为特发性,无确切病因。继发性 Pure red cell aplasia (PRCA) is a syndrome characterized by positive cell anemia, reticulocyte depletion, and marked reduction or absence of bone marrow erythroblasts, including congenital PRCA (Diamond-Blackfan anemia) and acquired PRCA. Among them, acquired PRCA can be divided into primary and secondary, primary PRCA may be related to autoimmune, also found in pre-leukemia, most of the idiopathic, no exact cause. Secondary