论文部分内容阅读
A Pd-catalyzed asymmetric aromative [4+3]-cyclization reaction of amino-trimethylenemethanes (TMM,1,3-dipoles) with fused 1-azadienes has been developed.This method enables access to the synthetically importance and biologically active benzofuran fused azepines and indeno-azepines in excellent efficiency and stereoselectivity (up to 95％ yield,99％ ee,＞19:1 dr).