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选择住院173例T2DM患者,其中合并NAFCD70例(脂肪肝组),对照组103例。结果NAFCD组腰围和臀围、收缩压、甘油三酯、空腹C肽高于非脂肪肝组,两组比较差异有统计学意义(P<0.01);NAFCD组餐后C肽和舒张压明显高于非脂肪肝组,两组比较差异有统计学意义(P<0.05);Logistic回归分析表明BMI、PBG、TG是2型糖尿病合并NAFCD形成的独立危险因素;合并NAFCD组MS发生率明显高于非脂肪肝组(P<0.01)。结论T2DM合并NAFCD与肥胖、脂代谢紊乱、血压升高、IR、MS密切相关。
173 hospitalized patients with T2DM were selected, including 70 NAFCD patients (fatty liver group) and 103 control patients. Results In NAFCD group, the waistline and hip circumference, systolic blood pressure, triglyceride and fasting C-peptide were higher than those in non-steatosis group (P <0.01). The postprandial C-peptide and diastolic blood pressure were significantly higher in NAFCD group Logistic regression analysis showed that BMI, PBG and TG were independent risk factors for the formation of type 2 diabetes mellitus and NAFCD. The incidence of MS was higher in NAFCD group than in non-steatohepatitis group (P <0.05) Non-fatty liver group (P <0.01). Conclusions T2DM with NAFCD is closely related to obesity, disorders of lipid metabolism, elevated blood pressure, IR and MS.