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采用间接免疫荧光染色法、MTT法分别检测52例乙型病毒性肝炎（简称乙肝）患者CD／CD值、NK和LAK细胞活性。结果表明，26例有乙肝病毒复制者（复制组）CD／CD值为1．36±0．34，26例无乙肝病毒复制者（非复制组）为2．99±0．61，两组差异有显著性意义（P＜0．05）。复制组LAK细胞活性为44．20±11．51，非复制组为67．90±9．82，两组比较差异有非常显著性意义（P＜0．01）。复制组NK细胞活性为40．01±12．48，非复制组68．80±9．82，两组比较差异有非常显著性意义（P＜0．01）。表明复制组细胞免疫功能明显低下，可为乙肝病毒复制者使用免疫促进剂治疗提供依据。
Indirect immunofluorescence staining and MTT assay were used to detect CD / CD, NK and LAK cell activity in 52 patients with viral hepatitis B (HBV). The results showed that the CD / CD value of 26 cases with HBV replication (replication group) was 1.36 ± 0.34, and 26 cases without HBV replication (non-replication group) was 2.99 ± 0.61. Two groups The difference was significant (P <0.05). The activity of LAK cells in the replication group was 44.20 ± 11.51 compared with 67.90 ± 9.82 in the non-replication group, with significant difference between the two groups (P <0.01). The NK cell activity in the replication group was 40.01 ± 12.48, while that in the non-replication group was 68.80 ± 9.82. There was significant difference between the two groups (P <0.01). Indicating that the cellular immune function was significantly lower in the replication group, which may provide a basis for the treatment of hepatitis B virus replication using immunostimulants.