本文测定了46例糖尿病病人及31例正常人全血谷胱甘肽过氧物酶(GSH—Px),过氧化氢酶(CAT)活力及血浆过氧化脂质(LPO)含量。糖尿病病人CAT,GSH—Px活力明显低于正常对照组,血浆LPO水平明显高于正常组。并发血管病变者改变更明显。此外,LPO值升高及GSH—Px,CAT活力降低与病人空腹血糖水平,病程及治疗方式均有一定关系。 In this study, we measured the glutathione peroxidase (GSH-Px), catalase (CAT) activity and plasma lipid peroxidation (LPO) levels in 46 diabetic patients and 31 normal subjects. The activities of CAT and GSH-Px in diabetic patients were significantly lower than those in normal controls, and the levels of LPO in plasma were significantly higher than those in normal subjects. Concomitant vascular lesions were more obvious changes. In addition, LPO value and GSH-Px, CAT activity decreased with the patient’s fasting blood glucose levels, duration and treatment have a certain relationship.