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目的通过623例尸体解剖,了解神经管畸形的检出率及病理特点。方法对我院2001年1月至2010年12月623例尸检作回顾性分析。结果 623例尸检中发现神经管畸形56例,占尸检8.99%,其中孕<28周胎儿为51.79%(29/56),围产儿(孕>28周至7天)48.21%(27/56),多为复合畸形。常见的神经管畸形为先天性脑积水、无脑儿、不同类型的脊柱裂及脑膜脑膨出。结论神经系统畸形的发生率高,神经管复合畸形的发生率高,神经管致死性畸形的发生率高。
Objective To investigate the detection rate and pathological features of neural tube defects by 623 cases of autopsy. Methods A retrospective analysis was performed on 623 autopsies from January 2001 to December 2010 in our hospital. Results 563 cases of neural tube defects were found in 623 autopsy cases, accounting for 8.99% of the autopsy cases, accounting for 51.79% (29/56) of pregnancies <28 weeks and 48.21% (27/56) of perinatuses (28 weeks to 7 days of pregnancy) Mostly compound deformity. Common neural tube defects congenital hydrocephalus, no brain children, different types of spina bifida and brain encephalocele. Conclusions The incidence of nervous system deformity is high, the incidence of neural tube complex deformity is high, and the incidence of neural tube fatal deformity is high.