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目的观察自拟中药方联合手术治疗结直肠癌并肠梗阻对患者肠梗阻段直径及生存率的影响。方法将196例结直肠癌并肠梗阻患者随机分为试验组和对照组各98例。试验组采用自拟中药方联合手术治疗,对照组采用常规治疗联合手术治疗。比较并评价这2组患者治疗前后结肠梗阻直径及手术治疗后的6、12、24个月生存率。结果手术前2组结肠梗阻直径差异无统计学意义(P>0.05)。手术后2组结肠梗阻直径均增大,且试验组大于对照组,差异均有统计学意义(P<0.05)。试验组患者治疗后6、12、24个月的生存率明显高于对照组,差异有统计学意义(P<0.05)。结论自拟中药方联合手术治疗结直肠癌并肠梗阻具有更好的临床疗效,可有效减轻患者的痛苦,提高患者的生活质量,值得临床推广应用。
Objective To observe the effect of self-made traditional Chinese medicine combined with surgery on colorectal cancer and intestinal obstruction on the diameter and survival rate of patients with intestinal obstruction. Methods 196 cases of colorectal cancer with intestinal obstruction were randomly divided into experimental group and control group, 98 cases each. The experimental group with self-prepared Chinese medicine combined with surgical treatment, the control group with conventional treatment combined with surgical treatment. The diameter of colonic obstruction and the 6, 12, and 24-month survival rates of the two groups before and after treatment were compared and evaluated. Results There was no significant difference in diameter of colonic obstruction between the two groups before operation (P> 0.05). After operation, the diameter of colonic obstruction in both groups increased, and the experimental group was larger than the control group, the difference was statistically significant (P <0.05). The survival rate of patients in test group was significantly higher than that of control group at 6, 12 and 24 months after treatment (P <0.05). Conclusion Self-made Chinese medicine combined with surgical treatment of colorectal cancer and intestinal obstruction has better clinical efficacy, which can effectively reduce the pain of patients and improve the quality of life of patients, it is worth clinical application.