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本文报道了一男性公民遭受一次(1965年12月)急性事故性超剂量的γ线和裂变中子辐射后的细胞遗传学随访观测结果。根据残存的骨髓干细胞(约3%)和事故后几天内观测的外周血液中淋巴细胞(经72小时培养)双着丝粒染色体发生率,估计该公民全身吸收剂量平均值接近5 Gy,但由于受照时的不均匀性,导致身体各部位(从头部的2Gy到左脚的50Gy)受照的剂量也不同。实验是在事故后的不同期间(从99个月至251个月共21年)采取静脉血样培养,46小时时收获细胞,
This article reports the results of a cytogenetic follow-up of a male citizen subjected to an acute accidental overdose of gamma-ray and fission neutron radiation (December 1965). The median systemic dose of this citizen is estimated to be near 5 Gy, based on the incidence of dicentric chromosomes from remaining bone marrow stem cells (approximately 3%) and peripheral blood lymphocytes (cultured for 72 hours) observed in the days following the accident As a result of inhomogeneity when illuminated, doses to different parts of the body (from 2Gy in the head to 50Gy in the left foot) are also different. The experiments were performed in venous blood samples during different post-accident periods (21 years from 99 months to 251 months), cells were harvested at 46 hours,