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1989年12月,在江苏省姬鼠型疫区进行EHF鼠间传播因素调查,并用免疫转印技术对同一鼠窝中鼠螨分离的EHF病毒进行抗原多肽分子量测定,结果一致。以每窝鼠数、鼠皮肤破损数、鼠窝残留食物EHF抗原阳性数和革螨数为自变量,以鼠窝鼠EHF抗原、抗体阳性率和EHF总感染率为因变量,分别进行多元线性回归分析。结果:4个自变量和3个因变量的回归关系有非常显著性意义;进一步进行回归方程显著性检验表明,在姬鼠型疫区鼠间传播因素中,以皮肤破损为主要因素;鼠间密切接触和革螨叮咬为次要因素:而与食入EHF抗原污染的食物关系不密切。
In December 1989, the EHF mice were investigated for the transmission of EHF in Jiangsu Province, and the molecular weight of the EHF virus isolated from mouse mites in the same litter was determined by immunotransfer technique. The results were consistent. EHF antigen, antibody positive rate and total infection rate of EHF were used as dependent variables in mice per mouse, mouse skin damage number, the positive number of EHF antigen and the number of gerbil mites in the mouse litter. The multivariate linearity regression analysis. Results: The regression relationship between the four independent variables and three dependent variables had significant significance. Further significant regression tests showed that the skin damage was the main factor in the intersexmunization among the mice in the Apodemus agrarius; Close contact with leather mites bites as a secondary factor: while eating food contaminated with EHF antigen is not closely related.