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多年来,研究人员一直在试图改造蚊子的基因以防止疟疾的传播。虽然先进技术一直支持在蚊子的基因组中引入基因改变,但是这些遗传变化如何在野生蚊子种群中传播仍然是一个问题。现在,基因驱动的概念正在为人们所知,基因改变可以比传统盂德尔遗传原理更快地传播开来,最终解决问题。基因驱动在种群中的扩散如果没有基因驱动,等位基因将通过传统的孟德尔遗传定律代代相传。也就是说,当仅携带一个等位基因拷贝的杂合个体与不携带该基因的个
For years, researchers have been trying to engineer mosquito genes to prevent the spread of malaria. Although advanced technologies have always supported the introduction of genetic changes into mosquito genomes, how these genetic changes propagate in wild mosquito populations remains a problem. Now that the concept of gene-driven is becoming known, genetic changes can spread faster than the traditional Yundel principle and ultimately solve the problem. Gene-Driven Diffusion in Populations Without gene-driven alleles will be passed on from generation to generation through traditional Mendelian laws of genetics. That is, when a heterozygous individual carrying only one allele copy and a non-carrying allele