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目的:观察654-2和吗啡静脉滴注对急诊肾绞痛患者的镇痛效果;。方法:选择武汉大学中南医院急诊就诊的肾绞痛患者1536例,自然分成2组,A组为2008年12月31日以前的患者,静脉应用654-2,B组为2009年以来患者,静脉应用吗啡,用药后不同时间点行疼痛程度评分,观察疼痛缓解的程度及不良反应。结果:B组患者3min后疼痛开始缓解,约6min疼痛明显减轻,10min基本缓解,无明显严重不良反应;A组患者20min时疼痛才开始缓解,约30min时疼痛缓解明显,部分患者出现急性尿潴留。2组比较差异有统计学意义。结论:肾绞痛患者静脉滴注吗啡镇痛迅速,起效快,无尿潴留副反应,是一种良好的镇痛方式。
Objective: To observe the analgesic effects of intravenous injection of 654-2 and morphine on patients with acute renal colic. Methods: 1536 cases of renal colic emergency treatment were selected from Central South Hospital of Wuhan University, which were divided into two groups. Group A was a patient before December 31, 2008, and a group of 654-2 was used intravenously. Patients in Group B were patients and veins Morphine was applied to evaluate the degree of pain relief and adverse reactions at different time points after treatment. Results: The pain in group B began to relieve after 3 minutes, the pain was relieved in about 6 minutes and was relieved in 10 minutes. There was no obvious serious adverse reaction in group B. In group A, the pain started to relieve at 20 minutes and was relieved in about 30 minutes. Some patients had acute urinary retention . The difference between the two groups was statistically significant. CONCLUSION: Intravenous morphine analgesia by intravenous drip in patients with renal colic is rapid, rapid onset and has no side effects of urinary retention. It is a good analgesic method.