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目的:为探讨双锁骨上区预防照射对食管癌预后的意义。材料与方法:1996年12月至1998年12月对65例食管癌病人进行了锁骨上预防照射,随机分成两组:双锁上预防照射组(33例)及对照组(32例)。均采用钴(60)照射。食管局部总量DT60～70Gy,双锁上DM50Gy。结果:双锁上预防照射组1、2、3年生存率似优于对照组,但无统计学差别。对照组放疗后有6％(2/32)出现锁上淋巴结转移。结论:锁骨上预防照射对防止淋巴结转移可能有效,但对生存率未见明确的影响。
Objective: To investigate the significance of double supraclavicular irradiation prevention on the prognosis of esophageal cancer. Materials and Methods: From December 1996 to December 1998, 65 patients with esophageal cancer were treated with supraclavicular prophylaxis. The patients were randomly divided into two groups: double-lock prevention group (33 cases) and control group (32 cases). All using cobalt (60) irradiation. Esophageal local total DT60 ~ 70Gy, double locked DM50Gy. Results: The 1, 2, 3-year survival rate of double-lock prevention group was better than that of control group, but there was no significant difference. In the control group, 6% (2/32) of the patients had lymphatic metastasis after radiotherapy. CONCLUSIONS: Supraclavicular prophylaxis may be effective in preventing lymph node metastases, but there is no clear effect on survival.