多器官功能障碍综合征(MODS)是指机体在遭受严重创伤、休克、感染等打击后,同时或序贯出现两个或两个以上脏器功能不全以致衰竭,不能维持内环境稳定的一种临床综合征。近年来,人们通过实验认识到高容量血液滤过(HVHF)可以显著改善血流动力学指标,清除炎症介质,改善肺功能。我们用高容量血液滤过治疗伴有急性肾功能衰竭的MODS, Multiple Organ Dysfunction Syndrome (MODS) refers to the body after suffering severe trauma, shock, infection, etc., at the same time or sequential occurrence of two or more organs insufficiency failure, can not maintain a stable environment Clinical syndrome. In recent years, people have realized through experiments that high-volume hemofiltration (HVHF) can significantly improve hemodynamic indicators, clear inflammatory mediators and improve lung function. We use high-volume hemofiltration in the treatment of MODS with acute renal failure,