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目的探讨慢性肝血吸虫病与肝细胞癌的关系。方法对９例血吸虫病肝纤维化（ＳＨＦ）并发肝细胞癌（ＨＣＣ）的病例作组织病理学观察。结果该９例分别占１９５９～１９９５年间病理诊断肝细胞癌的３．９％（９／２３１）和血吸虫病肝纤维化的４．６％（９／１９５）。镜下见早期血吸虫病肝纤维化与肝细胞癌并存。癌周肝病背景明显，其中３例可见典型毛玻璃样肝细胞，６例伴门脉性肝硬变（４例可见慢性活动性肝炎病灶）。结论慢性肝血吸虫病是一种促癌因素，它与乙型肝炎病毒（ＨＢＶ）可能有协同致癌作用
Objective To investigate the relationship between chronic hepatic schistosomiasis and hepatocellular carcinoma. Methods 9 cases of schistosomiasis liver fibrosis (SHF) complicated with hepatocellular carcinoma (HCC) were studied for histopathological observation. Results The 9 cases accounted for 3.9% (9/231) of pathological diagnosis of hepatocellular carcinoma from 1959 to 1995 and 4.6% (9/195) of hepatic fibrosis of schistosomiasis. Under the microscope, liver fibrosis and hepatocellular carcinoma coexist in early schistosomiasis. The background of hepatocarcinoma of the cancer was obvious, of which 3 cases showed typical glassy liver cells and 6 cases had portal cirrhosis (4 cases showed chronic active hepatitis lesions). Conclusion Chronic hepatic schistosomiasis is a cancer-promoting factor. It may have a synergistic carcinogenic effect with hepatitis B virus (HBV).