三唑醇(Triadimenol)是一种优良内吸性的广谱杀菌剂,用于处理各类作物种子时,防病效果显著。该化合物的分子式为C_(14)H_(18)N_3OCl,化学结构式如右。其中含有两个手性碳原子,应其有四种光学异构体。据文献报导,其中的两个非对映体之间的药效有明显的差别,有效体称为A体。A体的二个对映体之间的药效以(-)-A体为最佳有效体。鉴于了解A体的一对对映体的构型,对探讨其生物活性的作用机理及共与立体构型关系方面有重要意 Triadimenol is a broad-spectrum bactericide with excellent systemic properties for preventing disease when used on various crop seeds. The chemical formula of the compound is C_ (14) H_ (18) N_3OCl, and the chemical structural formula is as the right. Which contains two chiral carbon atoms, should have four optical isomers. According to the literature, there are obvious differences between the two diastereomers. The effective body is called A body. The pharmacophore between the two enantiomers of A (A) is the most effective one. Given the understanding of the configuration of a pair of enantiomers of A, it is important to explore the mechanism of action and the co-stereostructure relationship