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营养缺乏性佝偻病在我国仍是婴幼儿时期的一种常见病,多发病。它主要是由于体内维生素D(V_D)缺乏使肠道对钙、磷吸收减少,最终使骨矿化过程受干扰所致。造成体内V_D不足的传统观点是:(1)外源性V_D供给不足;(2)阳光暴露不足使皮肤内源性合成的V_D减少。近年来,人们还认识到母亲的营养状况、婴儿的生活习惯、喂养方式、某些微量元素及其它营养素的缺乏都可以直接或间接影响骨矿化的过程而致营养缺乏性佝偻病。本文就这些方面的研究作一综述。
Nutritional deficiency rickets in our country is still a common disease in infancy and frequently-occurring disease. It is mainly due to the lack of vitamin D (V_D) in the intestine to reduce the intestinal absorption of calcium and phosphorus, the final bone mineralization caused by interference. The traditional viewpoints that cause V_D deficiency in the body are: (1) insufficient supply of exogenous V_D; (2) insufficient sun exposure to reduce the VOD of the endogenous synthesis of the skin. In recent years, it has also been recognized that maternal nutritional status, infant habits, feeding practices, the lack of certain trace elements and other nutrients can directly or indirectly affect the process of bone mineralization and result in nutritional deficiency rickets. This article reviews the research of these aspects.