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用单向免疫电泳法测定83例冠心病患者和155例正常人血清ApoB水平。此外还同时测定血清TC、TG、LDL-C和HDL-C。结果表明:冠心病患者血清ApoB水平显著高于正常人,且这种差异在除去了有高脂血症的冠心病病人之后仍然有高度显著性。高TG冠心病病人ApoB显著高于高TG无冠心病对照组,而其他血脂在这两组间的差异无显著性。提示血清ApoB测定在冠心病诊断中的意义大于传统的血脂测定。
Serum ApoB levels in 83 patients with coronary heart disease and 155 normal individuals were determined by one-way immunoelectrophoresis. In addition, serum TC, TG, LDL-C and HDL-C were measured simultaneously. The results showed that: ApoB serum levels of patients with coronary heart disease were significantly higher than normal, and this difference in patients with coronary heart disease after removal of hyperlipidemia is still highly significant. Patients with high TG coronary heart disease ApoB was significantly higher than the high TG coronary heart disease control group, while other blood lipids in the two groups was no significant difference. Tip serum ApoB determination in the diagnosis of coronary heart disease is more than the significance of the traditional blood lipid determination.