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免疫球蛋白A(IgA)是Hereman(1959年)首次从血清中分离出来的抗体。1963年Feinstein 等在人和兔的体液如初乳、唾液、气管分泌物和泪液中,发现IgA 含量比血清高6～8倍。分泌性IgA(SIgA)广泛存在于人体外分泌液中。泪SIgA 是由反射泪腺或结膜浆液腺间质中浆细胞合成的2个IgA、泪腺腺泡上皮生产的1个分泌碎片(SC)和
Immunoglobulin A (IgA) is the first antibody that Hereman (1959) isolated from the serum. In 1963, Feinstein and others found in human and rabbit body fluids such as colostrum, saliva, tracheal secretions and tears, 6 to 8 times higher IgA levels than serum. Secretory IgA (SIgA) is widely present in human excretory fluid. SIgA of tears is composed of 2 IgA synthesized by plasma cells reflecting the lacrimal gland or conjunctival serous stroma, 1 secretory fragment (SC) produced by lacrimal gland acinar epithelium and