本实验应用透射电镜观察不同温度以及不同温度加抗肿瘤药物 (嘧福绿 )作用下的人卵巢癌细胞超微结构的变化 ,探讨热疗与化疗对肿瘤细胞作用的机理。实验结果表明 ,在高温下细胞代谢降低 ,肿瘤细胞的形态发生一系列恶性变化 ,且高热可能诱导肿瘤细胞的凋亡 ;热疗加化疗的协同作用则能加速肿瘤细胞的凋亡 ,使细胞的能量代谢更低 ,随着作用时间的延长 ,最终导致细胞死亡 In this experiment, transmission electron microscope was used to observe the ultrastructural changes of human ovarian cancer cells under the action of different temperatures and different temperatures plus anti-tumor drugs (pyrimofol), and to explore the mechanism of hyperthermia and chemotherapy on tumor cells. The experimental results show that under high temperature, the metabolism of the cells is reduced, and the morphogenesis of tumor cells undergoes a series of malignant changes, and hyperthermia may induce the apoptosis of tumor cells; the synergistic effect of hyperthermia plus chemotherapy can accelerate the apoptosis of tumor cells and make the cells Lower energy metabolism, eventually leading to cell death over time