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目的:探讨老年女性乳腺癌的最佳治疗方法及影响预后的因素。方法:回顾性分析1996年8月～2007年8月收治的老年女性乳腺癌临床资料。结果:89例患者中,83例手术治疗,其中乳腺癌根治术2例、改良根治55例、单纯乳腺切除术18例、肿瘤局部切除术8例;6例单纯放疗加内分泌治疗。8例于术后14个月至5年时局部复发,25例在随访10个月至5年时出现肺、肝、骨及脑转移,24例在随访14个月至6年时死于本病。5年生存率为86.7。结论:老年女性乳腺癌的临床治疗应以外科手术为主,内分泌治疗等为辅的综合治疗方案。
Objective: To explore the best treatment for breast cancer in elderly women and the factors affecting the prognosis. Methods: The clinical data of elderly women with breast cancer admitted from August 1996 to August 2007 were analyzed retrospectively. Results: Among the 89 patients, 83 cases were treated by surgery, including 2 cases of radical mastectomy, 55 cases of modified radical mastectomy, 18 cases of simple mastectomy and 8 cases of tumor resection. 6 cases received radiotherapy alone or endocrine therapy. Local recurrence occurred in 8 cases between 14 months and 5 years after operation, with lung, liver, bone and brain metastases in 25 cases at 10 months to 5 years of follow-up. Twenty-four patients died during the follow-up period of 14 months to 6 years disease. 5-year survival rate was 86.7. Conclusion: The clinical treatment of elderly women with breast cancer should be based on surgical treatment, endocrine therapy, supplemented by a comprehensive treatment program.