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心脑血管疾病的发病率和致死率居高不下,大量证据证实大部分急性血管事件是有易损斑块破裂所诱发的,而导致急性心脑血管事件的主要原因包括动脉粥样硬化斑块破裂及血栓形成,后者取决于斑块的不稳定性,即易损性。随着临床上对易损斑块认识的日益深入,如何在急性心脑血管事件发生前准确地识别出易损斑块并对患者进行积极有效的干预已成为迫切的问题,同时也是降低急性心血管事件发生率的关键。无创影像学检查方法不仅可以作为筛查动脉粥样硬化的工具,还可以对斑块进行定性评估和定量计算;目前部分无创性影像学手段在显示斑块内成分、鉴别易损斑块方面显示了良好的应用潜力,但仍无一种方法可以独立识别易损斑块并预测其进展,大多数方法只能评价易损斑块的某一特性。
The incidence of cardiovascular and cerebrovascular diseases and the high mortality rate, a large body of evidence to prove that most of the acute vascular events are induced by vulnerable plaque rupture, which led to the main causes of acute cardiovascular and cerebrovascular events, including atherosclerotic plaque Rupture and thrombosis, the latter depends on the plaque instability, that is, vulnerability. With the clinical understanding of vulnerable plaque increasingly in-depth, how to accurately identify vulnerable plaque before the occurrence of acute cardiovascular and cerebrovascular events and positive and effective intervention for patients has become an urgent problem, but also reduce the acute heart The key to the incidence of vascular events. Noninvasive imaging method not only can be used as a screening tool for atherosclerosis, but also can be qualitative and quantitative assessment of plaque; some of the current noninvasive imaging methods in the display of plaque components, the identification of vulnerable plaque However, there is still no way to identify and predict vulnerable plaque independently. Most of the methods can only evaluate a certain characteristic of vulnerable plaque.