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目的评价蕲蛇酶注射液治疗急性脑梗死的有效性和安全性。方法行自对照开放性研究,对52例发病1周内的脑梗死患者应用蕲蛇酶注射液0.75U,每日1次,共14天,观察治疗前后神经功能缺损评分和实验室指标,并进行疗效评定。结果治疗前后神经功能缺损评分和实验室指标均有显著差异,治疗效果:基本痊愈17.31%,显著进步55.77%,进步19.23%,总有效率为92.31%。未见严重不良反应。结论蕲蛇酶注射液治疗急性脑梗死安全有效。
Objective To evaluate the efficacy and safety of Acutobin injection in the treatment of acute cerebral infarction. Methods A self-controlled open-label study was conducted in 52 patients with cerebral infarction within 1 week after the onset of treatment. The animals were treated with 0.75u once daily for 14 days. Neurological impairment scores and laboratory parameters were observed before and after treatment Efficacy assessment. Results The scores of neurological deficits and laboratory indexes before and after treatment were significantly different. The therapeutic effects were: basically cured 17.31%, significant improvement 55.77%, improvement 19.23%, total effective rate 92.31%. No serious adverse reactions. Conclusion Acutus injection is safe and effective in the treatment of acute cerebral infarction.