贵州汉族人群21个非CODIS STR基因座的遗传多态性分析

来源 :贵州医科大学学报 | 被引量 : 0次 | 上传用户：fanw06

【摘要】

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目的调查贵州汉族人群21个非DNA检索系统(CODIS)的短串联重复序列(STR)基因座的遗传多态性,并评估其在法医学上的应用价值。方法选取301例贵州汉族无关个体血样,采用AGCU21+1

【作者】

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张红玲蔡鹏熊玲罗文钰杨美庆徐荣兰王启燕任峥季

【机构】

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贵州医科大学法医学院

【出处】

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贵州医科大学学报

【发表日期】

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2021年2期

【关键词】

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法医遗传学非DNA检索系统贵州汉族遗传多态性短串联重复序列亲权鉴定个体识别 forensic genetics non-combined DNA i

【基金项目】

：

贵州省高层次“百”层次创新型人才项目[黔科合平台人才(2020)6012],贵州省高技术产业化示范工程项目[黔发改高技(2016)1345],贵州省科技计划项目[黔科合支撑(2019)2825,黔科合支撑(2020)4Y057],贵州省科技计划基金项目[黔科合(2020)1Y353],大学生创新创业训练项目(DC201710660026,DC20195200903),贵州医科大学一流课程项目(YL

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目的调查贵州汉族人群21个非DNA检索系统(CODIS)的短串联重复序列(STR)基因座的遗传多态性,并评估其在法医学上的应用价值。方法选取301例贵州汉族无关个体血样,采用AGCU21+1荧光标记复合扩增系统对样本进行聚合酶链式反应(PCR),3500型全自动遗传分析仪对PCR扩增产物进行电泳分离,Gene Mapper ID-X 1.3软件进行STR基因分型,Modified-Powerstates软件包获得各基因座的等位基因频率、杂合度(H)、匹配概率(PM)、个体识别率(DP)、非父排除率(PE)

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贵州汉族人群21个非CODIS STR基因座的遗传多态性分析

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