论文部分内容阅读
目的 :观察黄芪注射液对糖尿病肾病 (DN)患者血、尿转化生长因子 β1(TGFβ1)的影响 ,探讨黄芪注射液治疗糖尿病肾病 (DN)的机制。方法 :分别测定黄芪注射液治疗组 ( 2 8例 ) ,对照组 ( 2 6例 )治疗前后血、尿TGFβ1尿白蛋白排泄率 (UAER)、血糖、糖化血红蛋白 (HbA1c)。结果 :黄芪注射液能明显降低DN患者血、尿TGFβ1水平 ,减少DN患者UAER ,具有降低HbA1c的作用。结论 :黄芪注射液对DN患者肾脏有保护作用 ,可能与其抑制DN患者TGFβ1有关。
Objective: To observe the effect of astragalus injection on blood and urine TGFβ1 in patients with diabetic nephropathy (DN) and to explore the mechanism of astragalus injection in treating diabetic nephropathy (DN). Methods: Blood and urinary TGFβ1 urinary albumin excretion rate (UAER), blood glucose and HbA1c were measured before and after treatment in astragalus injection group (28 cases) and control group (26 cases). Results: Astragalus injection can significantly reduce blood and urine TGFβ1 levels in patients with DN, reduce the UAER in patients with DN, with the role of reducing HbA1c. Conclusion: Astragalus injection has a protective effect on the kidney of DN patients, which may be related to the inhibition of TGFβ1 in DN patients.