补铁使缺铁性全血细胞减少症恶化:病例报告

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缺铁性贫血(IDA)是美国第二大营养缺乏症。大约有3300000例孕期妇女患有缺铁性贫血。缺铁性贫血常伴随血小板增多症,血小板的计数约为500~700×109/L。血小板数量增多是由于缺铁性贫血患者体内促红细胞生成素水平增高刺激了血小板的生成。虽然在缺铁性贫血患者中血小板减少症相对较少,但之前也有过报道。而更鲜为人知的是,补充了铁剂后血小板减少症反而恶化发展。也有报道说缺铁性贫血还可伴随轻度的白细胞减少症。但是,补铁治疗后白细胞计数的下降并没有报道。 Iron deficiency anemia (IDA) is the second malnutrition in the United States. About 3300000 pregnant women suffer from iron deficiency anemia. Iron deficiency anemia is often accompanied by thrombocytosis, platelet count is about 500 ~ 700 × 109 / L. The increased number of platelets is due to increased levels of erythropoietin in patients with iron deficiency anemia stimulated platelet production. Although there is relatively little thrombocytopenia in patients with iron deficiency anemia, it has also been reported before. What’s less known is that thrombocytopenia, which supplements the iron, worsens the development. It has also been reported that iron deficiency anemia may also be accompanied by mild leucopenia. However, the decline in white blood cell count after iron supplementation has not been reported.
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铁代谢1.铁的分布铁广泛分布于人体各种组织中。人体内铁可分为功能铁和贮存铁两部分,前者约占70%,包括血红蛋白铁、肌红蛋白铁、与转铁蛋白、乳铁蛋白结合的铁和含铁酶类等;
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