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1950年作者在加利福尼亚大学Valentine实验室开始研究与遗传性溶血性贫血有关的红细胞酶异常,第二年发现丙酮酸激酶缺乏的溶血性贫血症。回日本后,作者继续开展这方面的研究工作,在本文中介绍作者研究工作情况。丙酮酸激酶缺陷的发现 Selwyn和Dacie(1954)开展自家溶血实验,发现了所谓先天性非球形细胞溶血
In 1950, the author started researching hereditary hemolytic anemia-related erythrocyte abnormalities at Valentine’s Laboratory at the University of California, and found pyruvate kinase-deficient hemolytic anemia the following year. After returning to Japan, the author continues to carry out research work in this area, in this article describes the author’s research work. Discovery of Pyruvate Kinase Defects Selwyn and Dacie (1954) conducted their own hemolysis experiments and found that so-called congenital non-spherical hemolysis