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目的 :分析脑脊液细胞学检查对脑膜癌病的诊断价值。方法 :描述了 1 2例脑膜癌病患者的临床表现 ,辅助检查及确诊依据。结果 :1 2例脑膜癌病临床表现多样 ,主要表现为颅内高压和脑膜刺激征。颅脑 CT和 MRI多正常。脑脊液细胞学检查发现肿瘤细胞 ,异常细胞成簇排列 ,其胞体形态多变 ,核浆比例增大 ,胞浆呈嗜碱性 ,胞核形态不规则 ,核仁增多 ,核染色质浓染。常见有丝分裂等恶性肿瘤细胞固有特点。结论 :脑脊液细胞学检查发现癌细胞是脑膜癌病唯一生前确诊的依据
Objective: To analyze the diagnostic value of cerebrospinal fluid cytology in patients with meningeal carcinomatosis. Methods: Described in 12 cases of meningeal cancer clinical manifestations, laboratory tests and diagnosis based on. Results: The clinical manifestations of 12 cases of meningeal cancer were diverse, mainly manifested as intracranial hypertension and meningeal irritation. Brain CT and MRI more than normal. Cytological examination of cerebrospinal fluid showed that tumor cells and abnormal cells were clustered in clusters, the morphology of the cell body varied, the proportion of nuclear cytoplasm increased, basophilic cytoplasm, irregular nuclear morphology, increased nucleoli and chromatin condensation. Common malignant cells such as mitosis inherent characteristics. Conclusions: Cytological examination of cerebrospinal fluid revealed that cancer cells are the only basis of previous diagnosis of meningeal carcinomas