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[目的]了解和掌握厦门市流行性感冒活动状况及流行规律。[方法]建立流感监测点,定期采集流感样标本,用MDCK细胞分离病毒,血凝抑制试验鉴定分离毒株。用荧光定量PCR法检测2009年5月后的流感监测样本,获取核酸检测结果。[结果]2007年、2008年和2009年阳性率分别为4.8%(25/523)、5.6%(29/522)和13.2%(208/1 577)。2007年度为甲3和乙型同时流行,2008年度为甲1和乙型同时流行,2009年度因出现甲型H1N1流行,上半年以甲3型流行为主,下半年甲型H1N1流行为主。[结论]2007年至2008年我厦门市流感的流行情况较为平稳,不同型别的毒株表现出交替占优势的特征,活动的高峰主要集中在每年的4~8月。2009年全年流感病毒较前2年活跃,流行趋势上半年以甲3型为主,下半年以甲型H1N1为主。
[Objective] To understand and grasp the status and prevalence of influenza in Xiamen. [Methods] Influenza surveillance points were established, samples of influenza were collected periodically, viruses were isolated by MDCK cells, and the isolates were identified by hemagglutination inhibition test. Fluorescence quantitative PCR method was used to detect the influenza surveillance samples after May 2009 to obtain the nucleic acid detection results. [Results] The positive rates in 2007, 2008 and 2009 were 4.8% (25/523), 5.6% (29/522) and 13.2% (208/1 577), respectively. In 2007, A and B were prevalent at the same time. In 2008, A and B were simultaneously prevalent. In 2009, Influenza A (H1N1) prevailed in the first half of the year, mainly Influenza A (3) in the first half of the year, and H1N1 (H1N1) in the second half of the year. [Conclusion] The epidemic situation of influenza in Xiamen City was relatively stable from 2007 to 2008, and the strains of different genotypes showed the characteristics of alternating predominance. The peak of activity mainly concentrated in April ~ August of each year. Influenza virus in 2009 was more active than the previous two years. The first half of the epidemic was mainly type A 3, with type A H1N1 in the second half of the year.