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目的通过对慢性无症状乙型肝炎病毒表面抗原携带者(chronic asymptomatic HBsAgcarrier,CASC)血清总胆汁酸(total bile acid,TBA)、胆碱酯酶(cholinesterase,CHE)的分析,为其治疗提供依据。方法分析CASC血清中的TBA、CHE与正常对照组血清中TBA、CHE结果。结果在156例CASC的试验组中,TBA为(19.87±7.34)μmol/L,CHE为(4.12±1.88)kU/L;对照组TBA为(6.05±3.34)μmol/L,CHE为(10.29±1.26)kU/L。两组间比较差异有统计学意义(P<0.01)。试验组TBA高于正常参考值者47例,占30.8%;CHE低于正常参考值者25例,占16.0%。结论CASC应定期作包括TBA、CHE等多项肝功能指标的检测,并进行综合分析、合理治疗。
Objective To provide a basis for the treatment of chronic asymptomatic HBsAg carriers (CASC) by analyzing the levels of total bile acid (TBA) and cholinesterase (CHE) in chronic asymptomatic HBsAg carriers . Methods The serum TBA and CHE in CASC serum were analyzed. Results TBA was (19.87 ± 7.34) μmol / L and CHE was (4.12 ± 1.88) kU / L in 156 CASC experimental groups, and (6.05 ± 3.34) μmol / L and 10.29 ± 1.26) kU / L. The difference between the two groups was statistically significant (P <0.01). TBA in the test group was higher than the normal reference value in 47 cases, accounting for 30.8%; 25 cases of CHE lower than the normal reference value, accounting for 16.0%. Conclusions CASC should regularly carry out the detection of a number of liver function indexes including TBA and CHE, and carry out comprehensive analysis and reasonable treatment.