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目的:分析广州市番禺区人感染H7N9禽流感病例临床特征,为早期诊治提供依据。方法:对每例H7N9禽流感确诊病例开展流行病学调查,收集临床资料,分析其发病特征。结果:9例人感染H7N9禽流感确诊病例,年龄46岁~81岁,均为男性,5例有基础疾病,6例患者有禽类暴露史,9例患者均无典型的流感样症状,影像学表现均为快速进展的肺炎,从起病到出现重症肺炎需要机械通气中位数时间为5天,从起病到抗病毒治疗中位数时间为6天。6例进展为ARDS或多器官功能衰竭死亡。结论:在流感高发季节,对于有禽类暴露史的肺炎患者,即使无明显流感样症状,应高度警惕禽流感肺炎的可能,及早给予抗病毒治疗和严重并发症的防治。。
Objective: To analyze the clinical characteristics of H7N9 bird flu in Panyu District of Guangzhou City and provide evidence for early diagnosis and treatment. Methods: Epidemiological investigation was made on the confirmed cases of H7N9 bird flu in each case. The clinical data were collected and the incidence characteristics were analyzed. Results: Nine confirmed cases of H7N9 bird flu were aged 46 years to 81 years old. All of them were male. Five cases had underlying diseases. Six cases had history of bird exposure. None of the nine patients had typical flu-like symptoms. The performance of the rapid progression of pneumonia, from onset to severe pneumonia need mechanical ventilation median time for 5 days, from onset to antiviral treatment median time of 6 days. Six patients progressed to ARDS or multiple organ failure deaths. CONCLUSIONS: In the season of high flu, pneumonia patients with a history of avian influenza should be highly vigilant against the possibility of bird flu pneumonia and given anti-viral treatment and prevention of severe complications as early as possible, even though they are free from flu-like symptoms. .