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目的 观察脉心康胶囊对颈动脉粥样硬化治疗的临床疗效。方法 3 0例颈动脉粥样硬化病人 ,随机分为脉心康组与洛伐他汀组各15例。另外 15例颈动脉粥样硬化病人作为空白对照组。观察用药 6个月后对临床症状的影响 ,用彩色超声多普勒检测颈动脉内膜 -中膜厚度 (IMT)和斑块积分的变化。结果 两治疗组临床症状总疗效、总有效率无统计学意义 ,脉心康组显效率 (73 .3 3 % )明显优于洛伐他汀组 (2 6.67% )。两治疗组治疗后IMT与斑块积分均显著改善 ,两组间比较均无统计学意义 ;两治疗组对颈动脉粥样硬化的控制显效率、总有效率优于空白组。结论 脉心康胶囊与洛伐他汀均具有减轻和消退颈动脉粥样硬化的作用。
Objective To observe the clinical effect of Mai Xin Capsule in the treatment of carotid atherosclerosis. Methods Twenty-three patients with carotid atherosclerosis were randomly divided into two groups: 15 cases in each group. Another 15 patients with carotid atherosclerosis as a blank control group. The clinical symptoms were observed after 6 months of treatment. Changes in carotid intima - media thickness (IMT) and plaque score were examined by color Doppler sonography. Results The total effective rate and total effective rate of clinical symptoms in the two treatment groups were not statistically significant. The effective rate (73.33%) in the Xinxuankang group was significantly better than that in lovastatin group (2.667%). IMT and plaque score of both treatment groups after treatment were significantly improved, the two groups were no significant statistical significance; two treatment group carotid atherosclerosis markedly effective rate, the total effective rate was better than the blank group. Conclusion Both venous capsule and lovastatin can relieve and eliminate the effect of carotid atherosclerosis.