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自1951年发现给大鼠注射某些非离子性清洁剂可以产生高脂血症以未,这类物质已广泛用以评价某些降脂药物一特别是粘多糖类降脂药物的功效,从而也产生了间接估价甘油三酯(TG)进入血浆速度的方法。
Since 1951, it has been found that injecting certain non-ionic detergents into rats can produce hyperlipidemia. Such substances have been widely used to evaluate the efficacy of some lipid-lowering drugs, especially mucopolysaccharide-lowering drugs. This has also resulted in a method of indirectly assessing the rate of triglyceride (TG) entry into the plasma.