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研究发现,肥胖是导致预后不良的因素之一,即使在分子标志物提示预后较好的结肠癌患者中,亦是如此。一项未发表的涉及近5 000例患者的前瞻性研究数据表明,肥胖是导致结肠癌患者预后不良的因素之一,包括拥有与肿瘤良好预后相关标志物——肿瘤微卫星不稳定性(MSI)的结肠癌患者。美国癌症协会(ACS)肿瘤资源库的一项研究发现,相比身体质量指数(BMI,即用体重公斤数
The study found that obesity is one of the factors leading to poor prognosis, even in colon cancer patients whose molecular markers suggest a better prognosis. One unpublished data from a prospective study involving nearly 5,000 patients showed that obesity is one of the factors contributing to poor prognosis in patients with colon cancer, including having a tumor-associated microsatellite instability (MSI ) Of colon cancer patients. A study from the American Cancer Society (ACS) Tumor Resource Library found that compared to body mass index (BMI, ie, body weight kg